| Autor: |
Printseva OYu; Institute of Experimental Cardiology, Moscow, USSR., Peclo MM, Tjurmin AV, Gown AM |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of physiology [Am J Physiol] 1991 Oct; Vol. 261 (4 Suppl), pp. 21-2. |
| DOI: |
10.1152/ajpheart.1991.261.4.21 |
| Abstrakt: |
A monoclonal antibody, designated 10F3, that reacts with an antigen of molecular mass 90,000 Da has been developed by immunization of BALB/c mice with smooth muscle cells in long-term culture. The cells were originally isolated from fetal human aorta. The 10F3 was identified as an antibody that reacts with the ICAM-1 molecule. ICAM-1 is a mesenchymal antigen that is lost during differentiation of cells other than endothelium but is reexpressed by the intimal cells of vessels involved in atherogenesis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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