| Autor: |
Hatip-Al-Khatib I; Department of Pharmacology, Division of Internal Medicine, Faculty of Medicine, Pamukkale University, Kinikli, Denizli 20070, Turkey. izhatip@yahoo.com, Hatip FB, Yoshimitsu Y, Iwasaki K, Egashira N, Liu AX, Mishima K, Fujiwara M |
| Jazyk: |
angličtina |
| Zdroj: |
Phytotherapy research : PTR [Phytother Res] 2007 Mar; Vol. 21 (3), pp. 291-4. |
| DOI: |
10.1002/ptr.2050 |
| Abstrakt: |
The effects of Toki-shakuyaku-san (TSS) ingredients on acetylcholine (ACh) release in the dorsal hippocampus (DH) were investigated in intact and twice-repeated ischemic rats using in vivo microdialysis-HPLC. Moreover, the effect of TSS on blood flow was investigated in intact rats using laser Doppler flowmetry. TSS at 300 mg/kg p.o. increased ACh and blood flow after 40 min in intact rats. TSS also increased ACh in ischemic rats but to a lesser extent than in intact rats. These results could suggest that TSS-increased ACh and blood flow in DH may contribute in the cognition improving property of TSS. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Plný text