| Autor: |
Komano Y; Department of Medicine and Rheumatology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. y-komano.rheu@tmd.ac.jp, Kubota T, Wakabayashi S, Ochi S, Nonomura Y, Hagiyama H, Nanki T, Kohsaka H, Miyasaka N |
| Jazyk: |
angličtina |
| Zdroj: |
Modern rheumatology [Mod Rheumatol] 2004; Vol. 14 (5), pp. 410-3. |
| DOI: |
10.1007/s10165-004-0333-2 |
| Abstrakt: |
A 49-year-old woman was admitted to our hospital because of fever of unknown origin. The patient had long-lasting spiking fever, hepatosplenomegaly, pleural effusion, and skin rash. Laboratory tests showed marked leukocytosis and an extremely high serum ferritin level (240 000 ng/ml) accompanied by disseminated intravascular coagulation and hemophagocytic syndrome. Most of the patient's features were compatible with a diagnosis of adult-onset Still's disease (AOSD), the rash, however, was not a typical rheumatoid rash but multiforme erythema. Biopsy of a breast nodule revealed breast cancer, leading us to a diagnosis of paraneoplastic syndrome mimicking AOSD. Although this is a rare disorder, cases resembling the present one have been reported, indicating the importance of including paraneoplastic syndrome in the differential diagnosis of AOSD. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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