Myxedema coma in a patient with Down's syndrome.
| Autor: | Bansal D, Nanda A, Gupta E, Croker M, Williams ML, Bacchus A, Simmons D, Erbland M |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of the Arkansas Medical Society [J Ark Med Soc] 2006 Nov; Vol. 103 (5), pp. 112-3. |
| Abstrakt: | Introduction: hyroid dysfunction is common in Down's syndrome, most common being hypothyroidism. Longstanding, untreated hypothyroidism can lead to myxedema coma. Methods: Here we report a patient with Down's syndrome who presented with myxedema coma. Discussion: The three essential elements for the diagnosis of myxedema coma include altered mental status, defective thermoregulation and a precipitating event or illness; all of these were present in our patient. Also, very high TSH, low T3 and T4, and the rapid response to the treatment with levothyroxine confirmed the diagnosis. Conclusion: Patients with Down's syndrome should have regular screening for thyroid dysfunction. |
| Databáze: | MEDLINE |
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