Phase II study of pibenzimol in pancreatic cancer. A Southwest Oncology Group study.

Autor: Kraut EH; Ohio State University Health Center, Columbus., Fleming T, Segal M, Neidhart JA, Behrens BC, MacDonald J
Jazyk: angličtina
Zdroj: Investigational new drugs [Invest New Drugs] 1991 Feb; Vol. 9 (1), pp. 95-6.
DOI: 10.1007/BF00194556
Abstrakt: Twenty-three patients with advanced pancreatic adenocarcinoma were treated with Pibenzimol utilizing a daily intravenous schedule for five days. There were no objective responses seen. The major toxicity was pancreatic with grade 3 hyperglycemia in eleven patients. Pibenzimol is inactive in patients with advanced pancreatic adenocarcinoma.
Databáze: MEDLINE