A comparison of the relative rates of hemolysis induced by various fibrogenic and non-fibrogenic particles with washed rat erythrocytes in vitro.

Autor: Hefner RE Jr, Gehring PJ
Jazyk: angličtina
Zdroj: American Industrial Hygiene Association journal [Am Ind Hyg Assoc J] 1975 Oct; Vol. 36 (10), pp. 734-40.
DOI: 10.1080/0002889758507332
Abstrakt: Correlations between in vitro hemolytic activity and the in vivo fibrogenic activity of a number of particulate materials are demonstrated. Fibrogenic particles are capable of inducing hemolysis, while non-fibrogenic particles are not. It is suggested that particulates inducing a rate of hemolysis greater than 1 X 10(-4) min-1 may be fibrogenic.
Databáze: MEDLINE