Diagnosis of Paracoccidioidomycosis by detection of antigen and antibody in bronchoalveolar lavage fluids.

Autor: Marques-da-Silva SH; Department of Microbiology, Immunology, and Parasitology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Colombo AL, Blotta MH, Queiroz-Telles F, Balthazar AB, Lopes JD, de Camargo ZP
Jazyk: angličtina
Zdroj: Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2006 Dec; Vol. 13 (12), pp. 1363-6. Date of Electronic Publication: 2006 Oct 11.
DOI: 10.1128/CVI.00239-06
Abstrakt: Paracoccidioidomycosis (PCM) is a systemic infection caused by the fungus Paracoccidioides brasiliensis and is believed to be the leading cause of fungal pulmonary infection. In this study, we used an inhibition enzyme-linked immunosorbent assay to diagnose pulmonary PCM based on the detection of 43-kDa and 70-kDa molecules in bronchoalveolar lavage fluids. The results were compared with results obtained by classical methods for antibody detection.
Databáze: MEDLINE