Autor: |
Kotha S; Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai, India. srk@chem.iitb.ac.in, Shah VR, Halder S, Vinodkumar R, Lahiri K |
Jazyk: |
angličtina |
Zdroj: |
Amino acids [Amino Acids] 2007; Vol. 32 (3), pp. 387-94. Date of Electronic Publication: 2006 Oct 10. |
DOI: |
10.1007/s00726-006-0402-2 |
Abstrakt: |
Two synthetic routes to bis-armed-alpha-amino acid derivatives are described. The first route involves alkylation of dibromo derivatives with ethyl isocyanoacetate under phase-transfer catalysis (PTC) conditions. The second route uses a palladium-mediated Suzuki-Miyaura cross-coupling reaction between a DL-4-boronophenylalanine derivative and aromatic diiodo (or dibromo) compounds. |
Databáze: |
MEDLINE |
Externí odkaz: |
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