| Autor: |
Ivanovska I; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Muhoro CN, Irusta PM |
| Jazyk: |
angličtina |
| Zdroj: |
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2006 Sep; Vol. 6 (9), pp. 1033-42. |
| DOI: |
10.2174/138955706778195216 |
| Abstrakt: |
Apoptosis is a process that governs the elimination of unwanted, damaged, or infected cells in most organisms. Defects in its execution are associated with several diseases, including cancer. Herein, we discuss novel molecules with potential anti-tumor activity that target components of the apoptotic machinery, specifically Bcl-2 proteins, IAPs and caspases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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