Factors associated with H. pylori epidemiology in symptomatic children in Buenos Aires, Argentina.

Autor: Goldman C; Radioisotopes Laboratory, Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin 956-PB, Buenos Aires 1113, Argentina. cgold@ffyb.uba.ar., Barrado A, Janjetic M, Balcarce N, Cueto Rua E, Oshiro M, Calcagno ML, Sarrasague MM, Fuda J, Weill R, Zubillaga M, Perez-Perez GI, Boccio J
Jazyk: angličtina
Zdroj: World journal of gastroenterology [World J Gastroenterol] 2006 Sep 07; Vol. 12 (33), pp. 5384-8.
DOI: 10.3748/wjg.v12.i33.5384
Abstrakt: Aim: To determine prevalence of H pylori infection in symptomatic children in Buenos Aires, Argentina, and to investigate factors associated with H pylori positivity.
Methods: A total of 395 children with upper gastrointestinal symptoms referred to the Gastroenterology Unit of the Children Hospital "Sor Maria Ludovica" were evaluated for the presence of H pylori by the (13)C-Urea Breath Test ((13)C-UBT). A questionnaire was applied to the recruited population.
Results: Prevalence of H pylori infection was 40.0% in this population (mean age 9.97 +/- 3.1 years). The factors associated with H pylori positivity were number of siblings (P < 0.001), presence of pet cats (P = 0.03) and birds (P = 0.04) in the household, and antecedents of gastritis among family members (P = 0.01). After multivariate analysis, number of siblings [Odds ratio (OR) = 1.39; 95% CI, 1.20-1.61] and contact with pet cats (OR = 1.76; 95% CI, 1.00-3.09) remained as variables associated with H pylori infection.
Conclusion: The prevalence of H pylori infection in children with upper gastrointestinal symptoms in Argentina was similar to that reported in developed countries. Children from families with a higher crowding index and presence of pet cats have a higher risk of being colonized with H pylori.
Databáze: MEDLINE