Parametric evaluation of methotrimeprazine-midazolam-ketamine and methotrimeprazine-midazolam-ketamine-xylazine combination in dogs.
| Autor: | Santos GJ; Faculty of Veterinary Medicine and Zootechny, Laboratory of Veterinary Anesthesiology, Julio de Mesquita Filho University, Botucatu, São Paulo, Brazil., Hatschbach E, Mattos Júnior Ed, Massone F |
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| Jazyk: | angličtina |
| Zdroj: | Acta cirurgica brasileira [Acta Cir Bras] 2006 Sep-Oct; Vol. 21 (5), pp. 304-9. |
| Abstrakt: | Purpose: To evaluate the parameters of dogs anesthetized by different dissociative drugs protocols through continuous intravenous infusion. Methods: Thirty healthy dogs of both sexes were assigned randomly to three groups (G1, G2, and G3). G1 was administered with methotrimeprazine as a pre-anesthetic medication, intravenously midazolam-ketamine as bolus for induction and midazolam-ketamine by continuous intravenous infusion for a 60 minute-period of maintenance. G2: the same as for G1. plus an increase in the midazolam dose during maintenance. G3: the same treatment as for G2, plus the addition of xylazine during maintenance. Immediately after induction the anesthetic maintenance started, and measures were taken 15 minutes after pre-medication, at 10 minutes intervals, during maintenance (M0 to M7). Results: Bradycardia, atrioventricular blockage, bradypnea and hypoxemia were shown in G3. G1 and G2 showed a slight hypotension only. Conclusion: There were some advantages by using the continuous intravenous via: no parameters oscillation and reduction in the anesthetic recovery period. The increase in midazolam dose brought about little parametric variations which were greater when xylazine was used, with a consequent hypoxemia, bradyarrhytmia, and decrease in respiratory frequency and minute volume. |
| Databáze: | MEDLINE |
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