| Autor: |
Siwela AH; Department of Biochemistry, University of Zimbabwe., Nyathi CB, Chetsanga CJ, Hasler JA |
| Jazyk: |
angličtina |
| Zdroj: |
Biochemical pharmacology [Biochem Pharmacol] 1990 Jul 15; Vol. 40 (2), pp. 379-82. |
| DOI: |
10.1016/0006-2952(90)90703-n |
| Abstrakt: |
The covalent binding of [14C]acetylaminofluorene (AAF) to macromolecules in vivo and in vitro was measured in Schistosoma mansoni-infected and in non-infected mice. Liver microsomes from infected mice demonstrated a 42% decreased capacity to mediate covalent binding of AAF to DNA. In addition, the extent of binding of AAF to liver macromolecules in vivo was generally less in infected than non-infected mice. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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