[Results of radiation and chemoradiation therapy in esophageal cancer].

Autor: Azhigaliev NA, Kusherbaev SK, Sadykov SS, Asanov AA, Fel'dman SZ
Jazyk: ruština
Zdroj: Meditsinskaia radiologiia [Med Radiol (Mosk)] 1990 Jun; Vol. 35 (6), pp. 20-3.
Abstrakt: Eight therapeutic variants were worked out for 602 patients with esophageal cancer: 61 patients entered in the control group. The latter received routine radiation therapy. The results of therapy of 496 patients were studied. The most promising method was chemoradiotherapy using multifractionation of a daily dose of irradiation, the 4-year survival rate of 20% being achieved. For combination with radiation therapy the following schemes of chemotherapeutic agents were used bleomycin-methotrexate-prospidine, bleomycin-adriamycin-methotrexate, dactinomycin-methotrexate-prospidine, methotrexate-prospidine. Intensive detoxication therapy with parenteral feeding is recommended to decrease the frequency of complications and to improve therapy tolerance.
Databáze: MEDLINE