Safety and efficacy of modified radical lymph nodes dissection in patients with papillary thyroid cancer and clinically evident lymph nodes metastasis.

Autor:	Dimov RS; Department of General Surgery, University Hospital StGeorge, Medical University, Plovdiv, Bulgaria. rossen_dimov@hotmail.com, Deenichin GP, Damianliev RA, Ouchikov AP, Bacelov MH, Protohristov HT, Apostolov IR, Stefanov CS
Jazyk:	angličtina
Zdroj:	Folia medica [Folia Med (Plovdiv)] 2006; Vol. 48 (1), pp. 17-22.
Abstrakt:	Introduction: Papillary cancer of the thyroid gland is well known as a lymphotropic type of cancer. In more than 50 percent of all cases it metastasizes first and mainly in regional lymph nodes. The extent of surgical intervention remains a subject of controversy and discussions. Aim: The aim of our retrospective study was to evaluate efficacy and safety of modified radical lymph node dissection (MRND) in patients with papillary thyroid cancer (PTC). Patients and Methods: We performed a retrospective analysis of survival and quality of life of 19 patients who underwent surgery at the Department of General Surgery. All patients had papillary thyroid cancer and regional lymph nodes metastases. The results were compared to literature data on surgical interventions differing in extent and specifics. Results: Our analysis and its parallel with literature data revealed better survival rates and quality of life in patients who had undergone total thyroidectomy (TT) with modified radical lymph nodes dissection in comparison with those ones who had undergone total thyroidectomy with berry picking (BP). Conclusions: Modified radical lymph nodes dissection is an effective and comparatively safe procedure for the treatment of patients with papillary thyroid cancer and regional lymph nodes metastases. If adequately performed it ensures better quality of life, longer survival and improves further control on distant metastases.
Databáze:	MEDLINE
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