[Leydig cell tumor: our experience. Bibliographic review].

Autor: Rubio Tortosa I; Servicio de Urología, Hospital Doctor Peset, Valencia, España. nachorutor@hotmail.com, Rodrigo Guanter V, García Torrelles M, Verges Prosper A, Planelles Gómez J, San Juan de Laorden C
Jazyk: Spanish; Castilian
Zdroj: Archivos espanoles de urologia [Arch Esp Urol] 2006 Jun; Vol. 59 (5), pp. 467-72.
DOI: 10.4321/s0004-06142006000500002
Abstrakt: Objectives: To report the case-series of Leydig cell tumors diagnosed at our center, and to perform a bibliographic review on the topic.
Methods: Retrospective review of the clinical records of all patients with the diagnosis of Leydig cell tumor in our center over the last 12 years. We evaluated the clinical, diagnostic and therapeutic features, as well as outcomes.
Results: Four patients were diagnosed and treated in our department over this period. Mean patient age of the time of diagnosis was 51 years. Each of our cases have a different presentation. The two patients who underwent sperm analysis had azoospermia. None of the cases showed anomalous hormonal studies. Seventy-five percent of the cases showed ultrasound signs compatible with testicular neoplasia. In all of them surgical treatment was undertaken (inguinal orchyectomy); one of the patients underwent chemotherapy due to metastasis, having a good response. Mean follow-up is 76 months.
Conclusions: It is a rare testicular tumor. Inguinal orchyectomy is the treatment of choice. Its good outcome is remarkable.
Databáze: MEDLINE