| Autor: |
Iakovlev GM, Skorobogatov VI, Svistov AS, Mironova MI |
| Jazyk: |
ruština |
| Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1991 Sep-Oct; Vol. 54 (5), pp. 25-7. |
| Abstrakt: |
Phencarol, a blocker of H1-histamine receptors, is used as an antihistaminic agent. The antiarrhythmic effect of phencarol was detected and studied on experimental models of arrhythmias in non-anesthetized rabbits in a dose of 5 mg/kg intravenously. The drug was shown to possess the pronounced antiarrhythmic and protective properties on the models of calcium-chloride-, adrenaline- and strophanthine-induced arrhythmias and to exert no influence on aconitine-induced arrhythmia. Phencarol was demonstrated to have no cardiodepressive effect. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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