| Autor: |
Kumar G; Manonmaniam Sundaranar University, Sri Paramakalyani Centre for Environmental Sciences, Alwarkurichi, Tamil Nadu 627412, India., Banu GS, Murugesan AG, Pandian MR |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of ethnopharmacology [J Ethnopharmacol] 2006 Sep 19; Vol. 107 (2), pp. 304-7. Date of Electronic Publication: 2006 Jun 06. |
| DOI: |
10.1016/j.jep.2006.05.007 |
| Abstrakt: |
The hypoglycaemic effect of the aqueous extract of the bark of Helicteres isora L. (Sterculiaceae) was investigated in normal, glucose load conditions and streptozotocin (STZ)-induced diabetic rats. In normal rats, the aqueous extract of the bark of Helicteres isora L. (100 and 200 mg/kg/p.o.) significantly (P<0.001) reduced the blood glucose levels from 64.5-48.5 and 67-47 mg% 2h after oral administration of bark extract and also significantly lowered the blood glucose in STZ diabetic rats from 68-105 and 66-85.5 mg% 21 days after daily oral administration of the extract (P<0.001). The results suggested that the aqueous extract of bark of Helicteres isora L. possesses a potential hypoglycaemic effect in diabetic rats. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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