Autor: |
Taylor SW; Amylin Pharmaceuticals, Inc., 9360 Towne Centre Dr., San Diego California 92121, USA. staylor@amylin.com, Andon NL, Bilakovics JM, Lowe C, Hanley MR, Pittner R, Ghosh SS |
Jazyk: |
angličtina |
Zdroj: |
Journal of proteome research [J Proteome Res] 2006 Jul; Vol. 5 (7), pp. 1776-84. |
DOI: |
10.1021/pr0600982 |
Abstrakt: |
A novel approach is presented for the simultaneous identification and relative quantification of secreted peptides, particularly those that have been historically difficult to analyze in a concerted manner. Peptides exceeding 60 residues with various degrees of post-translational modification were identified on a liquid chromatographic time scale. The approach demonstrates high efficiency pattern-based recognition analysis of complex neuroendocrine peptide sets and enables rapid identification of biomarkers from biological material. |
Databáze: |
MEDLINE |
Externí odkaz: |
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