| Autor: |
Csiszár A; Universitatea de Medicină şi Farmacie Tg Mureş, Clinica de Oftalmologie., Baghiu MD, Horváth A, Neghirla A, Rusu M, Maki C, Elekes E |
| Jazyk: |
Romanian; Moldavian; Moldovan |
| Zdroj: |
Oftalmologia (Bucharest, Romania : 1990) [Oftalmologia] 2006; Vol. 50 (1), pp. 85-90. |
| Abstrakt: |
Osteopetrosis means a low function of osteoclasts, that induces bone resorption with a decrease in bone density. It has two genetic forms: a benign form with autosomal dominant inheritance (AD) and a malignant form with autosomal recessive inheritance (AR). The most successful therapy is bone marrow transplantation (rate of success 80%). We will present a case of malignant osteopetrosis of a five years old child. The late diagnosis (at 18 month) and the malignant evolution has made possible only palliative treatment, without surgical or ophthalmologic-neurosurgical implication. The prognosis is unfavorable with 70% survival to six years and 30% to ten years. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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