Asymmetric oscillation of adherent targeted ultrasound contrast agents.

Autor: Zhao S; Department of Biomedical Engineering, University of California, Davis, California 95616., Ferrara KW, Dayton PA
Jazyk: angličtina
Zdroj: Applied physics letters [Appl Phys Lett] 2005 Sep 26; Vol. 87 (13), pp. 1341031-1341033.
DOI: 10.1063/1.2061872
Abstrakt: With a lipid shell containing biotin, micron-sized bubbles bound to avidin on a porous and flexible cellulose boundary were insonified by ultrasound. The oscillation of these targeted microbubbles was observed by high-speed photography and compared to the oscillation of free-floating microbubbles. Adherent microbubbles were observed to oscillate asymmetrically in the plane normal to the boundary, and nearly symmetrically in the plane parallel to the boundary, with a significantly smaller maximum expansion in each dimension for bound than free bubbles. With sufficient transmitted pressure, a jet was produced traveling toward the boundary.
Databáze: MEDLINE