Changes in protein levels in perfusates of freely moving cats: relation to behavioral state.

Autor: Drucker-Colín RR, Spanis CW, Cotman CW, McGaugh JL
Jazyk: angličtina
Zdroj: Science (New York, N.Y.) [Science] 1975 Mar 14; Vol. 187 (4180), pp. 963-5.
DOI: 10.1126/science.167436
Abstrakt: Perfusates from the brains of freely moving cats, obtained by means of a push-pull cannula, contain high concentrations of proteins. The levels vary in a cyclic fashion and are higher during rapid eye movement sleep than during the waking state. The proteins represent a distinctive class of tissue protein and their changing levels appear to reflect an alteration in the protein content of the extracellular space of brain related to behavioral state.
Databáze: MEDLINE