| Autor: |
Kotton CN; Infectious Disease Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. ckotton@partners.org, Lankowski AJ, Hohmann EL |
| Jazyk: |
angličtina |
| Zdroj: |
Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2006 Oct; Vol. 56 (2), pp. 123-6. Date of Electronic Publication: 2006 May 24. |
| DOI: |
10.1016/j.diagmicrobio.2006.04.003 |
| Abstrakt: |
Rectal swabs are generally considered less sensitive than fecal culture, but there are no data directly comparing human rectal swabs with fecal samples for detection of Salmonella. A phase I clinical study of a live oral attenuated Salmonella typhimurium vaccine strain in volunteers receiving a large known inoculum provided the opportunity to compare concurrent rectal swab and fecal cultures. Of 155 paired samples from 9 volunteers, 65 (42%) were culture positive: 35 (54%) by both methods, 20 (31%) by fecal culture only, and 10 (15%) by swab only. When compared with fecal culture, rectal swabs were 64% sensitive and 90% specific. Rectal swabs are of moderate diagnostic utility for detection of Salmonella and may be useful when collection of fecal samples is impractical. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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