| Autor: |
Bloland PB; Malaria Branch, Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia 30333., Redd SC, Kazembe P, Tembenu R, Wirima JJ, Campbell CC |
| Jazyk: |
angličtina |
| Zdroj: |
Lancet (London, England) [Lancet] 1991 Mar 02; Vol. 337 (8740), pp. 518-20. |
| DOI: |
10.1016/0140-6736(91)91299-a |
| Abstrakt: |
The efficacy of co-trimoxazole for the treatment of Plasmodium falciparum parasitaemia in children younger than 5 years of age was evaluated in Malawi. 46 children with P falciparum parasitaemia, 37% of whom also met clinical criteria for a diagnosis of acute lower respiratory tract infection, were treated with 20 mg/kg co-trimoxazole twice daily for five days. Parasitaemia (mean clearance time 2.7 days) and symptoms were rapidly abolished and improvement was maintained during follow-up for 14 days. Co-trimoxazole may be an effective single treatment for febrile illness in young children in areas where malaria is endemic, resources are few, and diagnosis must rely on clinical findings alone. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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