[Effect of testosterone concentration on the intensity of 5alpha-dihydrotestosterone and 17beta-oestradiol formation].

Autor: Pechorskiĭ AV, Mazurov VI, Semiglazov VF, Karpishchenko AI, Udintsev AV
Jazyk: ruština
Zdroj: Tsitologiia [Tsitologiia] 2005; Vol. 47 (2), pp. 172-4.
Abstrakt: The culture of human male foreskin fibroblasts was incubated with various concentrations of testosterone in the medium. It has been shown that the minimum formation of 17beta-oestradiol and 5alpha-dihydrotestosterone occurs at physiological testosterone concentrations. Any deviation of testosterone concentration, both up and down, was accompanied by an increase in the formation of 17beta-oestradiol and 5alpha-dihydrotestosterone.
Databáze: MEDLINE