Polymeric core-shell nanoparticles for therapeutics.

Autor: Yang YY; Institute of Bioengineering and Nanotechnology, Singapore. yyyang@ibn.a-star.edu.sg, Wang Y, Powell R, Chan P
Jazyk: angličtina
Zdroj: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2006 May-Jun; Vol. 33 (5-6), pp. 557-62.
DOI: 10.1111/j.1440-1681.2006.04408.x
Abstrakt: 1. Nanobiotechnologies have recently attracted significant attention from chemists, biologists, engineers and pharmaceutical scientists. In particular, they have been widely applied to improve drug, protein/peptide and gene delivery. 2. This review presents recent advances in the field of drug, protein/peptide and gene delivery using natural and synthetic polymer nanoparticles and explains how polymeric nanoparticles are specifically designed to suit the needs for targeted delivery of small molecular drugs, proteins/peptides and genes. In addition, some of the challenges and prospects for these technologies are discussed.
Databáze: MEDLINE