Hyposensitization therapy of Parietaria-sensitive patients with a tyrosine adsorbed allergoid, Pollinex Parietaria (Bencard Parietaria).

Autor: Bonifazi F; Servizio Allergologia Respiratoria, Ospedale Generale Umberto I, Ancona, Italy., Antonicelli L, Bilò MB, Pucci S, Taylor IH, Wheeler AW, Youlten LJ
Jazyk: angličtina
Zdroj: Journal of investigational allergology & clinical immunology [J Investig Allergol Clin Immunol] 1991 Feb; Vol. 1 (1), pp. 37-44.
Abstrakt: Thirty patients suffering from allergy to Parietaria pollen were treated with either a new tyrosine-adsorbed allergoid of Parietaria judaica pollen (Pollinex Parietaria) or a commercially available alum-adsorbed extract (Alavac) as control. A reduced response to nasal provocation was seen in 7 out of 11 patients following treatment with Pollinex and 1 out of 10 after control treatment. 9 out of 11 and 3 out of 10, respectively, showed reduced skin test activity. Patients who received Pollinex tended to have fewer nasal symptoms during the pollen season. Pollinex induced larger increases in P. judaica-specific IgG antibody than did the control product. Side effects of therapy were similar between the two groups of patients. Pollinex Parietaria thus shows good potential for the control of allergy to Parietaria pollen.
Databáze: MEDLINE