| Autor: |
Stadnikova NM, Kleĭmenova EV, Grankina EP, Pylev LN |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy onkologii [Vopr Onkol] 1991; Vol. 37 (11-12), pp. 1077-81. |
| Abstrakt: |
Sodium selenite given in drinking water in a 4 ppm solution during the whole experiment was found to significantly inhibit pleural carcinogenesis induced in Wistar rats by intrapleural injection of chrysotile-asbestos powder (20 mg three times, monthly, in 0.5 ml of physiologic saline). Mesothelioma of the pleura was induced in 20.5%. However, chrysotile alone induced tumor in 43.8%. Sodium selenite failed to influence carcinogenesis in other sites. Possible mechanisms of sodium selenite action are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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