| Autor: |
Logvinov SV; Department of Histology, Embryology, and Cytology, Siberian State Medical University, Tomsk., Gerasimov AV, Kostyuchenko VP |
| Jazyk: |
angličtina |
| Zdroj: |
Neuroscience and behavioral physiology [Neurosci Behav Physiol] 2006 Jun; Vol. 36 (5), pp. 463-6. |
| DOI: |
10.1007/s11055-006-0040-x |
| Abstrakt: |
Light and electron microscopic methods were used to analyze changes in secretory neurons in the supraoptic (SON) and paraventricular (PVN) nuclei in the hypothalamus in 100 adult male rats at time points from the first minutes to 180 days after 48 hours of full-time exposure to bright light. At the early time points after exposure, the cellular formulae of the SON and PVN shifted towards functionally active neurons with minimal quantities of secretory granules, large nuclei and nucleoli, low RNA contents, small numbers of rough endoplasmic reticulum cisterns, vacuoles, and lysosomes in the perikarya. The number of cells depositing secretion was greater than in controls at 24 h in the SON and PVN and at 10 days in the SON. Normalization of the cellular formula and the structural organization of the protein-synthesizing apparatus of PVN neurons occurred at 10-30 days, with normalization in the SON at 30-180 days. These data provide evidence that the range of plasticity of neurons in the PVN on exposure to full-time bright light was more significant than that in the SON. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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