| Autor: |
Jones LH; Sandwich Laboratories, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK. lyn.jones@pfizer.com, Dupont T, Mowbray CE, Newman SD |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2006 Apr 13; Vol. 8 (8), pp. 1725-7. |
| DOI: |
10.1021/ol060316x |
| Abstrakt: |
[reaction: see text] A concise and efficient route to the construction of a 5-aryloxyimidazole has been developed. The key step was the selective O-arylation of a 2,4-dimethoxybenzyl-protected imidazolone. The final compound is a potent inhibitor of HIV reverse transcriptase. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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