Non-invasive cardiac evaluation in heart failure patients using magnetic resonance imaging: a feasibility study.

Autor: Shors SM; Department of Radiology, Division of Cardiology, Feinberg School of Medicine, Northwestern University, 251 East Huron Street, Chicago, IL, 60611-3864, USA. sshors@yahoo.com, Cotts WG, Pavlovic-Surjancev B, Gheorghiade M, Carr JC, McCarthy RM, Pereles SF, Finn PJ
Jazyk: angličtina
Zdroj: Heart failure reviews [Heart Fail Rev] 2005 Dec; Vol. 10 (4), pp. 265-73.
DOI: 10.1007/s10741-005-7540-6
Abstrakt: Background: To assess the feasibility of a fast, flow-insensitive magnetic resonance imaging (MRI) protocol in heart failure patients for the evaluation of cardiac function, cardiovascular anatomy, and myocardial viability.
Methods and Results: Thirty-two consecutive patients with left ventricular (LV) systolic dysfunction and 13 control subjects were prospectively evaluated with MRI. The exam consisted of cine imaging with a steady-state free precession sequence, followed by time-resolved, three-dimensional angiography and delayed, contrast-enhanced imaging. Multiple LV parameters were evaluated, and the heart failure and control results were compared. In 12 patients, MRI-determined ejection fractions were compared to echocardiographic values. Additionally, a qualitative analysis of the cine images was performed. The cardiac MR evaluation yielded diagnostic-quality images in all subjects. Mean imaging time was 37 min. MRI demonstrated significant differences between the heart failure and control subjects in all parameters assessed (p < 0.05). MRI-determined ejection fractions correlated strongly with echocardiographic values (R = 0.75), although the limits of agreement were wide (-17.3%-18.3%).
Conclusions: Using fast, flow-insensitive imaging techniques, MRI is feasible in heart failure for the derivation of more independent indices of cardiac status than any other non-invasive test. Although further investigation is warranted, MRI may prove uniquely helpful in heart failure diagnosis and management.
Databáze: MEDLINE
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