Identification of a diuretic hormone of Locusta migratoria.

Autor: Lehmberg E; Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel., Ota RB, Furuya K, King DS, Applebaum SW, Ferenz HJ, Schooley DA
Jazyk: angličtina
Zdroj: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1991 Sep 16; Vol. 179 (2), pp. 1036-41.
DOI: 10.1016/0006-291x(91)91923-z
Abstrakt: We have isolated a peptide from brains and corpora cardiaca of Locusta migratoria which is immunologically related to the diuretic hormone of Manduca sexta. We determined its structure as a 46 amino acid linear peptide with 43-50% identity to the M. sexta hormone. Moreover, we showed that the new peptide functions as a diuretic hormone in L. migratoria, stimulating urine production by Malpighian tubules and elevating levels of cAMP in tubules.
Databáze: MEDLINE