Clinical correlates of left ventricular hypertrophy in black patients with arterial hypertension.

Autor: Lepira FB; Department of Medical Physiology, Faculty of Health Sciences, University of Stellenbosch, Tygerberg, South Africa., Kayembe PK, M'buyamba-Kabangu JR, Nseka MN
Jazyk: angličtina
Zdroj: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners [Cardiovasc J S Afr] 2006 Jan-Feb; Vol. 17 (1), pp. 7-11.
Abstrakt: Objective: To assess the relationship between the lipid profile, other cardiovascular risk factors and left ventricular hypertrophy (LVH) in black hypertensive patients.
Materials and Methods: We undertook a cross-sectional study of a case series at the hypertension clinic, University of Kinshasa Hospital. Lipids, lipoproteins and other cardiovascular risk factors were analysed in 100 consecutive hypertensive patients. Left ventricular hypertrophy was assessed by 12-lead electrocardiography (ECG) using Cornell voltage index.
Results: Forty-eight hypertensive patients, 26 men and 22 women, had LVH. With univariate analysis, the patients with LVH were older (age 52 +/- 9 vs 45 +/- 9 years; p /= 1.03 mmol/l (adjusted OR 0.19; 95% CI: 0.057-0.651), plasma glucose >/= 6.11 mmol/l (adjusted OR 0.19; 95% CI: 0.046- 0.828), or on treatment for hypertension (adjusted OR 0.23; 95% CI: 0.082-0.645) had a lower risk for cardiac damage compared to their respective control groups.
Conclusion: LVH is a common complication in Congolese hypertensives. Dyslipidaemia, high plasma glucose levels, the duration of hypertension and being on antihypertensive therapy appear to be the main predictors of hypertensive cardiac damage.
Databáze: MEDLINE
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