[Cutaneous metastasis of Crohn's disease].

Autor: Masmoudi A; Service de dermatologie, CHU Hédi Chaker, Sfax, Tunisie. masmoudiabd@yahoo.fr, Abdelmaksoud W, Bouassida S, Khabir A, Charfeddine A, Fourati H, Boudawara T, Baklouti S, Krichen M, Turki H, Zahaf A
Jazyk: francouzština
Zdroj: Presse medicale (Paris, France : 1983) [Presse Med] 2006 Feb; Vol. 35 (2 Pt 1), pp. 230-2.
DOI: 10.1016/s0755-4982(06)74558-4
Abstrakt: Introduction: Involvement of the skin in Crohn's disease is rare. We report the case of a young woman presenting cutaneous nodules revealing a Crohn's disease.
Case Report: R. K. a 19 year old woman was admitted the impatient clinic for a 2 week history of nodular lesions of the extremities. Simultaneously, she had watery diarrhoea and abdominal pain associated with a bad general condition and fever. Skin examination showed ulcerated lesions with a non infiltrated inflammatory bader of the left food and the right calf associated with an abscess of the left forearm. Skin biopsy showed an inflammatory infiltrate of the deep dermis with tuberculoid noncaseating granulomas. Colonoscopy demonstrated multiple ulcers, a "globlestone appearance" of the glow and segmental glitis. Colonoscopy was followed by a peritonitis which made steroid therapy questionable. Meanwhile, the patient underwent a colonostomy and was fed intravenously, the skin lesions resolved. A follow up colonoscopy demonstrated colon polyps, and the biopsy of the colon showed features of colitis and "follicular" duodenitis which was in concordance with the diagnosis of Crohn's disease.
Commentaries: Usually, cutaneous lesions in Crohn's disease are consistent with nodules and granulomatous fissures of the grain. Involvement of the mucosa is rare. We report the case of "metastatic" localisation of nodular abscesses in Corhn disease. Improvement of cutaneous lesions might be explained by the nonuse of the digestive track allowed by the parenteral supplementation.
Databáze: MEDLINE
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