| Autor: |
Reccius CH; School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA. hcf3@cornell.edu, Mannion JT, Cross JD, Craighead HG |
| Jazyk: |
angličtina |
| Zdroj: |
Physical review letters [Phys Rev Lett] 2005 Dec 31; Vol. 95 (26), pp. 268101. Date of Electronic Publication: 2005 Dec 21. |
| DOI: |
10.1103/PhysRevLett.95.268101 |
| Abstrakt: |
We investigated compression and ensuing expansion of long DNA molecules confined in nanochannels. Transverse confinement of DNA molecules in the nanofluidic channels leads to elongation of their unconstrained equilibrium configuration. The extended molecules were compressed by electrophoretically driving them into porelike constrictions inside the nanochannels. When the electric field was turned off, the DNA strands expanded. This expansion, the dynamics of which has not previously been observable in artificial systems, is explained by a model that is a variation of de Gennes's polymer model. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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