Albendazole trial at 15 or 30 mg/kg/day for subarachnoid and intraventricular cysticercosis.

Autor: Göngora-Rivera F; Department of Neurology, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico., Soto-Hernández JL, González Esquivel D, Cook HJ, Márquez-Caraveo C, Hernández Dávila R, Santos-Zambrano J
Jazyk: angličtina
Zdroj: Neurology [Neurology] 2006 Feb 14; Vol. 66 (3), pp. 436-8. Date of Electronic Publication: 2005 Dec 28.
DOI: 10.1212/01.wnl.0000195887.63124.dc
Abstrakt: Thirty-six patients with subarachnoid and intraventricular cysticercosis were randomly assigned to receive albendazole at 15 or 30 mg/kg/day plus dexamethasone for 8 days. Results favored a higher dose, with larger cyst reduction on MRI at 90 and 180 days and higher albendazole sulfoxide levels in plasma. An albendazole course at 30 mg/kg/day combined with corticosteroids is safe and more effective than the usual dose. A single treatment was insufficient in intraventricular and giant cysts.
Databáze: MEDLINE