Reduction of 2,3-dihydroisoxazoles to beta-amino ketones and beta-amino alcohols.

Autor: Aschwanden P; Laboratorium für Organische Chemie, ETH Hönggerberg, CH-8093 Zürich, Switzerland., Kvaernø L, Geisser RW, Kleinbeck F, Carreira EM
Jazyk: angličtina
Zdroj: Organic letters [Org Lett] 2005 Dec 08; Vol. 7 (25), pp. 5741-2.
DOI: 10.1021/ol052540c
Abstrakt: [chemical reaction: see text]. We report the reduction of 2,3-dihydroisoxazoles to beta-amino ketones and beta-amino alcohols. The latter are obtained in high diastereoselectivity with preference for the syn isomer.
Databáze: MEDLINE