| Autor: |
Morelli F; Hypertriglyceridemia Department, Immunohematology Services, San Martino University Hospital, Genova--Italy. federico.morelli@hsanmartino.it, Carlier P, Giannini G, De Luigi MC, Dejana AM, Ruzzenenti MR |
| Jazyk: |
angličtina |
| Zdroj: |
The International journal of artificial organs [Int J Artif Organs] 2005 Oct; Vol. 28 (10), pp. 1025-31. |
| DOI: |
10.1177/039139880502801010 |
| Abstrakt: |
Several trials have assessed the link between low-density lipoprotein cholesterol (LDL) and the development of coronary heart disease (CHD). LDL apheresis provides an effective role in treating patients with familial hypercholesterolemia (FH) and in preventing the progression of coronary artery disease (CAD). Five different techniques of LDL apheresis are in current use: immunoadsorption (IMA), dextran sulphate-cellulose adsorption (DSA), heparin extracorporeal LDL precipitation system (HELP), double filtration plasmapheresis (DFPP) or lipidfiltration and direct adsorption of lipoprotein using hemoperfusion (DALI). All methods are efficient,but their cost restricts LDL apheresis to the treatment of FH. Indications could include other diseases, but controlled trials are still lacking. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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