| Autor: |
Droste S; Department of Analytical Chemistry, University of Wuppertal, Wuppertal, Germany., Schellenträger M, Constapel M, Gäb S, Lorenz M, Brockmann KJ, Benter T, Lubda D, Schmitz OJ |
| Jazyk: |
angličtina |
| Zdroj: |
Electrophoresis [Electrophoresis] 2005 Nov; Vol. 26 (21), pp. 4098-103. |
| DOI: |
10.1002/elps.200500326 |
| Abstrakt: |
We describe the successful coupling of CEC and capillary HPLC with the recently developed atmospheric-pressure laser ionization (APLI) method. APLI is suitable for selectively and sensitively ionizing nonpolar aromatic compounds at ambient pressure for subsequent mass-selective detection. The polycyclic aromatic hydrocarbons used as analytes are first separated either by CEC on a silica-based monolithic column or by capillary HPLC. The eluent, along with a sheath flow, is volatilized by microelectrospray and then selectively ionized by excimer laser (KrF*) radiation via two-photon excitation. A QTOF-MS is used as mass-selective detector. This interface combination makes soft ionization of thermally labile nonpolar aromatic analytes possible. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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