Electroencephalographic background desynchronization during cerebral blood flow reduction.

Autor: Cursi M; Department of Clinical Neurophysiology, San Raffaele Hospital, Milan, Italy., Meraviglia MV, Fanelli GF, Chiesa R, Tirelli A, Comi G, Minicucci F
Jazyk: angličtina
Zdroj: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2005 Nov; Vol. 116 (11), pp. 2577-85. Date of Electronic Publication: 2005 Oct 07.
DOI: 10.1016/j.clinph.2005.06.026
Abstrakt: Objective: The aim of this study is to evaluate the usefulness of a spectral function detecting cerebral hypoperfusion.
Methods: Continuous electroencephalographic monitoring was employed during 47 consecutive carotid endarterectomies. Patients were assigned to 3 different groups according to the entity of electroencephalographic changes during carotid clamping (major changes: group A; moderate changes: group B; no change: group C). The desynchronization function, indicating the reduction of the 8-15 Hz band power, and the desynchronization index were calculated.
Results: Group A function decreased within 20s from clamping, with a constant slope (7.14). Desynchronization indexes were: 76.85% (group A), 40.23% (group B) and 15.29% (group C). Difference among groups was statistically significant (P < 0.0001). A case of syncope due to asystole is also reported, showing the same pattern in the descending phase of the function.
Conclusions: The stereotyped time course of the desynchronization function describes the cerebral reaction to significant blood flow reduction. Values of desynchronization index exceeding 65% seem to correctly detect patients with cerebral hypoxic risk.
Significance: The analysis of the 8-15 Hz band desynchronization is helpful in the evaluation of cerebral hypoperfusion during carotid endarterectomy. This method could be employed in monitoring different clinical situations of ischemia.
Databáze: MEDLINE
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