| Autor: |
Al-Qahtani A; Zoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia., Siddiqui YM, Bekhit AA, El-Sayed OA, Aboul-Enein HY, Al-Ahdalb MN |
| Jazyk: |
angličtina |
| Zdroj: |
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2005 Oct; Vol. 338 (10), pp. 484-7. |
| DOI: |
10.1002/ardp.200500147 |
| Abstrakt: |
A screening study was conducted to examine the effect of a series of synthesized pyrazoloquinoline derivatives on the growth of Leishmania donovani promastigotes. Sixteen compounds were tested, ten of which showed an inhibitory effect on the growth of promastigotes. Compound 1 demonstrated potent antileishmanial activity, followed by compounds 3 and 7. Some compounds showed less significant activities, while others exhibited little or no activity. Some of these compounds may be potential candidates for future treatment of leishmaniasis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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