| Autor: |
Serfaty MA; Drug and Alcohol Unit, Plummer Court, Newcastle upon Tyne, NE1 6UR, UK., Lawrie A, Smith B, Brind AM, Watson JP, Gilvarry E, Bassendine MF |
| Jazyk: |
angličtina |
| Zdroj: |
Drug and alcohol review [Drug Alcohol Rev] 1997 Dec; Vol. 16 (4), pp. 339-47. |
| DOI: |
10.1080/09595239700186721 |
| Abstrakt: |
Of 1728 patients attending a regional drug and alcohol clinic, 202 were considered at risk of hepatitis C virus (HCV). Forty-nine per cent (99/202) agreed to testing-67% (67) were HCV antibody positive. Age and a history of needle sharing was the significant factor associated with positive HCV status. Patients on methadone maintenance medication were more-likely to have been HCV positive, but significantly (p = 0.005) less likely to have shared needles in the previous year. Seventy-three per cent (49/67) attended for follow-up at a "liver clinic". Fifty per cent were infected with genotype 1a. Eighteen patients were biopsied and all were abnormal, ranging from mild hepatitis to severe fibrotic hepatitis. Attendance for medical follow-up was poor, which emphasizes the importance of preventative measures such as methadone maintenance programmes for reducing the spread of HCV. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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