| Autor: |
Dossetor JB, Liburd EM, Kovithavongs T, Higgins MR, Pazderka V |
| Jazyk: |
angličtina |
| Zdroj: |
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association [Proc Eur Dial Transplant Assoc] 1979; Vol. 16, pp. 442-8. |
| Abstrakt: |
Details are presented of three aspects of immunological monitoring in a single instance of severe irreversible rejection of a renal allograft. Rejection is associated with strong evidence of lymphocyte mediated cytotoxicity (LMC). During this period reduced responsiveness of recipient cells to stimulation in vitro by donor cells is observed; this is more reduced than is responsiveness to random cells. Donor-specific suppressor cells also develop, as detected in two systems. It is postulated that the data are evidence that competition exists between different agressive and suppressive subpopulation of recipient lymphocytes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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