| Autor: |
Bastos MA Jr; Disciplina de Diabetes e Metabologia, Hospital Universitário Pedro Ernesto, Universidade Estadual do Rio de Janeiro, RJ. mabastosjr@terra.com.br, Oliveira MM, de Castro SH, Cunha EF, Moraes ER, Ruzzani F, Gomes MB |
| Jazyk: |
portugalština |
| Zdroj: |
Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2005 Apr; Vol. 49 (2), pp. 271-7. Date of Electronic Publication: 2005 Sep 12. |
| DOI: |
10.1590/s0004-27302005000200014 |
| Abstrakt: |
We evaluated retrospectively 34 patients with post-kidney transplant diabetes (PTDM) (group 1) and 68 submitted to renal transplant without PTDM (group 0) to determine the prevalence and risk factors for developing PTDM in patients followed at the Hospital Universitário Pedro Ernesto. The prevalence of PTDM was 7.4%. Group 1 patients were older at data collection (p<0.005) and at transplantation (p<0.005). Among them there was a higher frequency of cadaver donors (p= 0.023) and hypercholesterolemia (p= 0.006), and a lower frequency of arterial hypertension (p<0.0001). We observed a trend to higher frequency of positive sorology for C hepatitis (p= 0.057) and use of tacrolimus (p= 0.069) in group 1 as compared to group 0. The most important risk factors for developing PTDM (by logistic regression) were the age at renal transplant [OR= 1.099, IC 95% (1.045-1.156), p= 0.0001] and positive sorology for C hepatitis [OR= 3.338, IC 95% (1.205-9.248), p= 0.020]. We conclude that the prevalence of PTDM in our hospital was similar to that found in the literature and that the patients who developed PTDM presented a higher prevalence of traditional risk factors for PTDM, like older age and positive C virus hepatitis sorology, comparing to controls. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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