Preventive Pap-smears: balancing costs, risks and benefits.

Autor: van Ballegooijen M; Department of Public Health and Social Medicine, Erasmus University Rotterdam, The Netherlands., Habbema JD, van Oortmarssen GJ, Koopmanschap MA, Lubbe JT, van Agt HM
Jazyk: angličtina
Zdroj: British journal of cancer [Br J Cancer] 1992 Jun; Vol. 65 (6), pp. 930-3.
DOI: 10.1038/bjc.1992.195
Abstrakt: The pattern of spontaneous screening for cervical cancer by general practitioners and gynaecologists in The Netherlands is compared with an efficient screening policy resulting from a cost-effective study. Spontaneous screening tends to start and stop too early in a woman's life, and leaves too many women overscreened or unprotected. The combination in young age of a low incidence of invasive cancer and a high incidence of regressive lesions explains relative ineffectiveness and harmfulness of present screening practice. When screening would take place between ages 30 and at least 60, with intervals of about 5 years, as many lives could be saved for half the costs and with only 60% of the unnecessary referrals and treatments. Much attention should be paid to the coverage of the target population. Therapeutic follow-up policies for dysplastic lesions should be restrained.
Databáze: MEDLINE