Longitudinal clinical and serological survey of abdominal angiostrongyliasis in Guaporé, southern Brazil, from 1995 to 1999.

Autor: Graeff-Teixeira C; Laboratório de Biologia Parasitária, Faculdade de Biociências, Pontificia Universidade Católica do Rio Grande do Sul, Av. Ipiranga 6690, HSL 2o andar, sala 20, 90690-900 Porto Alegre, Rio Grande do Sul, Brazil. graeteix@pucrs.br, Goulart AH, Brum Cde O, Laitano AC, Sievers-Tostes C, Zanini GM, Bered PL, Morassutti A, Geiger S, Abrahms-Sandi E, Oliveira FT, Maurer RL, Aguiar LF, Garrido CT, da Silva AC, Rodriguez R, Schulz-Key H, Agostini AA
Jazyk: angličtina
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2005 Jul-Aug; Vol. 38 (4), pp. 310-5. Date of Electronic Publication: 2005 Aug 03.
DOI: 10.1590/s0037-86822005000400006
Abstrakt: Abdominal angiostrongyliasis is a zoonotic infection caused by Angiostrongylus costaricensis, a nematode with an intra-vascular location in the mesentery. Our objective was to address several aspects of the natural history of this parasitosis, in a longitudinal clinical and seroepidemiological study. A total of 179 individuals living in a rural area with active transmission in southern Brazil were followed for five years (1995-1999) resulting in yearly prevalence of 28.2%, 4.2%, 10%, 20.2% and 2.8% and incidences of 0%, 5.9%, 8% and 1.5%, respectively. Both men and woman were affected with higher frequencies at age 30-49 years. In 32 individuals serum samples were collected at all time points and IgG antibody reactivity detected by ELISA was variable and usually persisting not longer than one year. Some individual antibody patterns were suggestive of re-infection. There was no association with occurrence of abdominal pain or of other enteroparasites and there was no individual with a confirmed (histopathologic) diagnosis. Mollusks were found with infective third-stage larvae in some houses with an overall prevalence of 16% and a low parasitic burden. In conclusion, abdominal angiostrongyliasis in southern Brazil may be a frequent infection with low morbidity and a gradually decreasing serological reactivity.
Databáze: MEDLINE