Synthesis and antitumor properties of 7-deoxy-7-[(cis- and trans-3-aminocyclohexane)thio]carminomycinone.
| Autor: | Essery JM, Doyle TW, Schreiber RH |
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| Jazyk: | angličtina |
| Zdroj: | Journal of medicinal chemistry [J Med Chem] 1979 Nov; Vol. 22 (11), pp. 1425-8. |
| DOI: | 10.1021/jm00197a029 |
| Abstrakt: | The synthesis of analogues of carminomycin in which the daunosamine group has been replaced by (cis- and trans-3-aminocyclohexane)thio moieties is described. The new compounds were found to exhibit none of the antitumor or antibiotic activity associated with carminomycin. |
| Databáze: | MEDLINE |
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