| Autor: |
Kidwai M; Department of Chemistry, University of Delhi, Delhi 110007, India. kidwai_chemistry@yahoo.co.uk, Saxena S, Khan MK, Thukral SS |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2005 Oct 01; Vol. 15 (19), pp. 4295-8. |
| DOI: |
10.1016/j.bmcl.2005.06.041 |
| Abstrakt: |
A simple, clean, environmentally benign route to the synthesis of 2-amino-chromenes is described using K2CO3 as a green catalyst in water under microwave irradiation. This implies a convenient route avoiding the usage of hazardous organic solvents and organic bases. This technique requires only water in both the reaction step and workup, thus rendering the whole procedure into a truly ecofriendly green protocol. All the synthesized compounds were shown to possess antibacterial activity as tested in vitro against standard strains of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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