[The variability of clinical presentation of chronic obstructive pulmonary disease in patients with hereditary alpha-1 antitrypsin deficiency].

Autor: Kuca P; Oddziału Intensywnej Terapii Pneumonologiczno--Kardiologicznej, Warszawa., Kamiński D, Campbell E, Kołakowski J, Goljan-Geremek A, Puścińska E, Bieleń P, Nowiński A, Wojda E, Hawryłkiewicz I, Sliwiński P, Górecka D
Jazyk: polština
Zdroj: Pneumonologia i alergologia polska [Pneumonol Alergol Pol] 2004; Vol. 72 (9-10), pp. 420-3.
Abstrakt: Four patients with alpha-1 antitrypsin (alpha-1 AT) deficiency are presented: one woman with severe (phenotype PiZ) and 3 men with moderate (phenotype PiMZ) deficiency of alpha-1 AT. The variability of clinical presentation of hereditary emphysema is described. In all patients tobacco smoking history, spirometric and 6-minutes walking tests as well as HRCT of the lung were performed and compared. The influence of smoking on the functional status is underlined.
Databáze: MEDLINE