Intra- and interpatient variability of the hsp65 and 16S-23S intergenic gene region in Mycobacterium abscessus strains from patients with cystic fibrosis.

Autor: König B; Institute of Medical Microbiology, Otto-von-Guericke University Magdeburg, Leipzigerstr. 44, D-39120 Magdeburg, Germany. brigitte.koenig@medizin.uni-magdeburg.de, Tammer I, Sollich V, König W
Jazyk: angličtina
Zdroj: Journal of clinical microbiology [J Clin Microbiol] 2005 Jul; Vol. 43 (7), pp. 3500-3.
DOI: 10.1128/JCM.43.7.3500-3503.2005
Abstrakt: To establish the exact pathogenic role of Mycobacterium abscessus in cystic fibrosis (CF), molecular tests are required for accurate identification. Forty-eight M. abscessus isolates from seven patients with CF were analyzed by sequence analysis for sequence variants within the hsp65 gene and the 16S-23S intergenic sequence (ITS). We detected two different hsp65 genes and correspondingly two ITS sequevars belonging to M. abscessus type I and type II.
Databáze: MEDLINE