| Autor: |
Dos Santos JG Jr; Department of Psychobiology, Neurophysiology Laboratory, Federal University of São Paulo, Rua Botucatu, 862, 5 andar, 04023-900, São Paulo, Brazil. Guistos@lycos.com, Blanco MM, Do Monte FH, Russi M, Lanziotti VM, Leal LK, Cunha GM |
| Jazyk: |
angličtina |
| Zdroj: |
Fitoterapia [Fitoterapia] 2005 Sep; Vol. 76 (6), pp. 508-13. |
| DOI: |
10.1016/j.fitote.2005.04.017 |
| Abstrakt: |
The hydroalcoholic extract of Equisetum arvense (HAE) tested at the doses of 200 and 400 mg/kg showed a significant activity on the open-field, enhanced the number of falls in the rota-rod reducing the time of permanence in the bar and increased the sleeping time (46% and 74%) in the barbiturate-induced sleeping time. In the pentylenetetrazole-seizure, it increased the first convulsion latency, diminished the severity of convulsions, reduced the percentage of animals which developed convulsion (50% and 25%) and protected animals from death. On the contrary, in the elevated plus maze, the doses 50, 100 and 150 mg/kg did not affect the evaluated parameters. Thus, HAE presented anticonvulsant and sedative effects. Phytochemical analysis detected the presence of tannins, saponins, sterols and flavonoids. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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